Reactome | AJUBA binds centrosome-associated AURKA

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AJUBA binds centrosome-associated AURKA Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10691293
displayName	AJUBA binds centrosome-associated AURKA
eventOf	[Pathway:R-XTR-2565942] Regulation of PLK1 Activity at G2/M Transition - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-XTR-2574840] AJUBA facilitates AURKA autophosphorylation - Xenopus tropicalis
inferredFrom	[Reaction:R-HSA-2574845] AJUBA binds centrosome-associated AURKA - Homo sapiens
input	[Complex:R-XTR-2574827] Centrosome:AURKA [cytosol] [EntityWithAccessionedSequence:R-XTR-2564698] wtip [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	AJUBA binds centrosome-associated AURKA
output	[Complex:R-XTR-2574836] Centrosome:AURKA:AJUBA [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-2574845
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-2565942] Regulation of PLK1 Activity at G2/M Transition
(precedingEvent)	[Reaction:R-XTR-2574840] AJUBA facilitates AURKA autophosphorylation
(inferredTo)	[Reaction:R-HSA-2574845] AJUBA binds centrosome-associated AURKA

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