Reactome | Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region]

Schema > Complex > Entries

compartment	[Compartment:81347] chromosome, centromeric region
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10690933
displayName	Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region]
hasComponent	[Complex:R-XTR-2467801] Cleaved Cohesin [chromosome, centromeric region] 2 × [Complex:R-XTR-375305] Kinetochore [cytosol] 30 × [Complex:R-XTR-190599] Microtubule [cytosol] [DefinedSet:R-XTR-2468261] PDS5 [chromosome, centromeric region] [EntityWithAccessionedSequence:R-XTR-2468269] phospho-cdca5 [chromosome, centromeric region] 2 × [OtherEntity:R-ALL-1638792] Sister Centromere [chromosome] [EntityWithAccessionedSequence:R-XTR-2577088] wapl [chromosome, centromeric region]
inDisease	false
inferredFrom	[Complex:R-HSA-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Homo sapiens
maxDepth	8
name	Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules
producedByEvent	[Reaction:R-XTR-2467809] ESPL1 (Separase) cleaves centromeric cohesin - Xenopus tropicalis
schemaClass	Complex
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-2467806
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[Reaction:R-XTR-2467809] ESPL1 (Separase) cleaves centromeric cohesin
(inferredTo)	[Complex:R-HSA-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region]

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