Reactome | Recruitment of VAV and BTK to p-SLP-76

Schema > Reaction > Entries

Recruitment of VAV and BTK to p-SLP-76 Show undefined attributes

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10690646
displayName	Recruitment of VAV and BTK to p-SLP-76
eventOf	[Pathway:R-XTR-2424491] DAP12 signaling - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2424481] Recruitment of VAV and BTK to p-SLP-76 - Homo sapiens
input	[EntityWithAccessionedSequence:R-XTR-197948] BTK [cytosol] [Complex:R-XTR-2424460] p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] [SimpleEntity:R-ALL-179838] PI(3,4,5)P3 [plasma membrane] [EntityWithAccessionedSequence:R-XTR-430152] vav3 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Recruitment of VAV and BTK to p-SLP-76
output	[Complex:R-XTR-2424461] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG:VAV:BTK:PIP3 [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-2424481
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-2424491] DAP12 signaling
(inferredTo)	[Reaction:R-HSA-2424481] Recruitment of VAV and BTK to p-SLP-76

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