Reactome | Haptoglobin-related Protein binds Hemoglobin

Schema > Reaction > Entries

Haptoglobin-related Protein binds Hemoglobin Show undefined attributes

category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10689452
displayName	Haptoglobin-related Protein binds Hemoglobin
eventOf	[Pathway:R-XTR-2168880] Scavenging of heme from plasma - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2168889] Haptoglobin-related Protein binds Hemoglobin - Homo sapiens
input	2 × [DefinedSet:R-XTR-2168876] Hemoglobin Dimer [extracellular region] [Complex:R-XTR-2168878] HPR:APOL1:APOA1:HDL3 [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	Haptoglobin-related Protein binds Hemoglobin Formation of Trypanosome Lytic Factor1
output	[Complex:R-XTR-2168857] Hemoglobin:HPR:APOL1:APOA1:HDL3 [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-2168889
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-2168880] Scavenging of heme from plasma
(inferredTo)	[Reaction:R-HSA-2168889] Haptoglobin-related Protein binds Hemoglobin

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