Reactome | Translocation of caspase-3 to the nucleus

Schema > Reaction > Entries

category	transition
compartment	[Compartment:13231] nuclear envelope
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10667283
displayName	Translocation of caspase-3 to the nucleus
eventOf	[Pathway:R-XTR-140342] Apoptosis induced DNA fragmentation - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-211219] Translocation of caspase-3 to the nucleus - Homo sapiens
input	[Complex:R-XTR-350870] Caspase-3 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Translocation of caspase-3 to the nucleus
output	[Complex:R-XTR-211223] active caspase-3 [nucleoplasm]
precedingEvent	[Reaction:R-XTR-114252] Cleavage of Procaspase-3 by the apoptosome - Xenopus tropicalis
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-211219
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-XTR-140342] Apoptosis induced DNA fragmentation
(inferredTo)	[Reaction:R-HSA-211219] Translocation of caspase-3 to the nucleus

Cite Us!