Reactome | Translocation of YAP1:ZO-2 (TJP2) to the nucleus

Schema > Reaction > Entries

category	transition
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10688478
displayName	Translocation of YAP1:ZO-2 (TJP2) to the nucleus
eventOf	[Pathway:R-XTR-2028269] Signaling by Hippo - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2064406] Translocation of YAP1:ZO-2 (TJP2) to the nucleus - Homo sapiens
input	[Complex:R-XTR-2064400] YAP1:TJP2 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Translocation of YAP1:ZO-2 (TJP2) to the nucleus
output	[Complex:R-XTR-2064401] YAP1:TJP2 [nucleoplasm]
precedingEvent	[Reaction:R-XTR-2064421] YAP1 binds ZO-2 (TJP2) - Xenopus tropicalis
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-2064406
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-XTR-2028269] Signaling by Hippo
(inferredTo)	[Reaction:R-HSA-2064406] Translocation of YAP1:ZO-2 (TJP2) to the nucleus

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