Reactome | (WASPs, WAVE):G-actin:ARP2/3 binds F-actin

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(WASPs, WAVE):G-actin:ARP2/3 binds F-actin Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10688214
displayName	(WASPs, WAVE):G-actin:ARP2/3 binds F-actin
eventOf	[Pathway:R-XTR-5663213] RHO GTPases Activate WASPs and WAVEs - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-XTR-2197690] Detachment of WASP/WAVE - Xenopus tropicalis
inferredFrom	[Reaction:R-HSA-2029466] (WASPs, WAVE):G-actin:ARP2/3 binds F-actin - Homo sapiens
input	[Polymer:R-XTR-201877] F-actin [cytosol] [Complex:R-XTR-442565] WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	(WASPs, WAVE):G-actin:ARP2/3 binds F-actin
output	[Complex:R-XTR-2029140] Mother filament:branching complex [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-2029466
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-5663213] RHO GTPases Activate WASPs and WAVEs [Pathway:R-XTR-2029482] Regulation of actin dynamics for phagocytic cup formation
(precedingEvent)	[Reaction:R-XTR-2197690] Detachment of WASP/WAVE
(inferredTo)	[Reaction:R-HSA-2029466] (WASPs, WAVE):G-actin:ARP2/3 binds F-actin

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