Reactome | B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG

Schema > Reaction > Entries

B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG Show undefined attributes

catalystActivity	[CatalystActivity:10687929] N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity of B3GNT1,2,3,4,7 [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10687931
displayName	B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG
eventOf	[Pathway:R-XTR-2022854] Keratan sulfate biosynthesis - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-XTR-2046265] B4GALTs transfer Gal to the keratan chain - Xenopus tropicalis
inferredFrom	[Reaction:R-HSA-2025724] B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG - Homo sapiens
input	[DefinedSet:R-XTR-2046271] Gal-glycan-protein [Golgi lumen] [SimpleEntity:R-ALL-914003] UDP-GlcNAc [Golgi lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG
output	[SimpleEntity:R-ALL-425969] H+ [Golgi lumen] [DefinedSet:R-XTR-2046187] Keratan(1)-PG [Golgi lumen] [SimpleEntity:R-ALL-205687] UDP [Golgi lumen]
precedingEvent	[Reaction:R-XTR-2025723] B4GALTs transfer Gal to the N-glycan precursor - Xenopus tropicalis [Reaction:R-XTR-744231] SLC35D2 exchanges UDP-GlcNAc for UMP - Xenopus tropicalis [Reaction:R-XTR-741450] SLC35A3 exchanges UDP-GlcNAc for UMP - Xenopus tropicalis [Reaction:R-XTR-742354] SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen - Xenopus tropicalis
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-2025724
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-2022854] Keratan sulfate biosynthesis
(precedingEvent)	[Reaction:R-XTR-2046265] B4GALTs transfer Gal to the keratan chain
(inferredTo)	[Reaction:R-HSA-2025724] B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG