Reactome | ERK/MAPK targets

Schema > Pathway > Entries

created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10729500
displayName	ERK/MAPK targets
eventOf	[Pathway:R-XTR-198725] Nuclear Events (kinase and transcription factor activation) - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-XTR-198746] ERK1/2/5 activate RSK1/2/3 - Xenopus tropicalis [Pathway:R-XTR-202670] ERKs are inactivated - Xenopus tropicalis
inferredFrom	[Pathway:R-HSA-198753] ERK/MAPK targets - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	ERK/MAPK targets
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-198753
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-XTR-198725] Nuclear Events (kinase and transcription factor activation) [Pathway:R-XTR-450282] MAPK targets/ Nuclear events mediated by MAP kinases
(inferredTo)	[Pathway:R-HSA-198753] ERK/MAPK targets