Reactome | Vitamin B1 (thiamin) metabolism

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Vitamin B1 (thiamin) metabolism Show undefined attributes

created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10729486
displayName	Vitamin B1 (thiamin) metabolism
eventOf	[Pathway:R-XTR-196849] Metabolism of water-soluble vitamins and cofactors - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:80321] thiamine-containing compound metabolic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-XTR-199626] SLC19A2/3 transport extracellular THMN to cytosol - Xenopus tropicalis [Reaction:R-XTR-196761] 2xTPK1:Mg2+ phosphorylates THMN - Xenopus tropicalis [Reaction:R-XTR-965067] THTPA:Mg2+ hydrolyzes ThTP to TDP - Xenopus tropicalis [Reaction:R-XTR-8875838] SLC25A19 transports ThDP from cytosol to mitochondrial matrix - Xenopus tropicalis
inferredFrom	[Pathway:R-HSA-196819] Vitamin B1 (thiamin) metabolism - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Vitamin B1 (thiamin) metabolism
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-196819
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-196849] Metabolism of water-soluble vitamins and cofactors
(inferredTo)	[Pathway:R-HSA-196819] Vitamin B1 (thiamin) metabolism

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