Reactome | p75NTR signals via NF-kB

Schema > Pathway > Entries

created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10729438
displayName	p75NTR signals via NF-kB
eventOf	[Pathway:R-XTR-193704] p75 NTR receptor-mediated signalling - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:139811] negative regulation of apoptotic process
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-XTR-209543] p75NTR recruits signalling complexes - Xenopus tropicalis [Pathway:R-XTR-209560] NF-kB is activated and signals survival - Xenopus tropicalis
inferredFrom	[Pathway:R-HSA-193639] p75NTR signals via NF-kB - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	p75NTR signals via NF-kB
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-193639
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-XTR-193704] p75 NTR receptor-mediated signalling
(inferredTo)	[Pathway:R-HSA-193639] p75NTR signals via NF-kB

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