Reactome | Cyclin E:p-T160-CDK2 [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-XTR-188373] CCNE:p-T160-CDK2:hypophosphorylated RB1 [nucleoplasm] - Xenopus tropicalis
consumedByEvent	[Reaction:R-XTR-188386] Association of Rb with Cyclin E:Cdk2 complexes - Xenopus tropicalis
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10652063
displayName	Cyclin E:p-T160-CDK2 [nucleoplasm]
hasComponent	[DefinedSet:R-XTR-68373] Cyclin E [nucleoplasm] [EntityWithAccessionedSequence:R-XTR-187967] phospho-p-T160-CDK2 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-188362] Cyclin E:p-T160-CDK2 [nucleoplasm] - Homo sapiens
maxDepth	3
memberOf	[DefinedSet:R-XTR-8848491] CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] - Xenopus tropicalis
name	Cyclin E:p-T160-CDK2
negativelyRegulates	[NegativeRegulation:10720020] Negative regulation by 'Cyclin E:p-T160-CDK2 [nucleoplasm]'
producedByEvent	[Reaction:R-XTR-188390] Cyclin E:CDK2-mediated phosphorylation of RB1 - Xenopus tropicalis [Reaction:R-XTR-188350] CAK-mediated phosphorylation of Cyclin E:Cdk2 - Xenopus tropicalis
schemaClass	Complex
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-188362
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(regulator)	[NegativeRegulation:10720020] Negative regulation by 'Cyclin E:p-T160-CDK2 [nucleoplasm]'
(output)	[Reaction:R-XTR-188390] Cyclin E:CDK2-mediated phosphorylation of RB1 [Reaction:R-XTR-188350] CAK-mediated phosphorylation of Cyclin E:Cdk2
(input)	[Reaction:R-XTR-188386] Association of Rb with Cyclin E:Cdk2 complexes
(hasComponent)	[Complex:R-XTR-188373] CCNE:p-T160-CDK2:hypophosphorylated RB1 [nucleoplasm]
(hasMember)	[DefinedSet:R-XTR-8848491] CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm]
(inferredTo)	[Complex:R-HSA-188362] Cyclin E:p-T160-CDK2 [nucleoplasm]