Reactome | TGFB1:TGFBR2:TGFBR1 [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10725608] protein serine/threonine kinase activity of TGFBR2 dimer:TGFB1 dimer:TGFBR1 dimer [plasma membrane] [CatalystActivity:10661552] transforming growth factor beta receptor activity, type II of TGFB1:TGFBR2:TGFBR1 [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-XTR-170843] TGFBR2 phosphorylates TGFBR1 - Xenopus tropicalis
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10661551
displayName	TGFB1:TGFBR2:TGFBR1 [plasma membrane]
hasComponent	[Complex:R-XTR-170852] Dimeric TGFB1 [extracellular region] [Complex:R-XTR-170864] TGFBR1 homodimer [plasma membrane] [Complex:R-XTR-170866] TGFBR2 homodimer [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-206874] TGFBR2 dimer:TGFB1 dimer:TGFBR1 dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-170840] TGFB1:TGFBR2:TGFBR1 [plasma membrane] - Homo sapiens
maxDepth	3
name	TGFB1:TGFBR2:TGFBR1
schemaClass	Complex
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-170840
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(physicalEntity)	[CatalystActivity:10725608] protein serine/threonine kinase activity of TGFBR2 dimer:TGFB1 dimer:TGFBR1 dimer [plasma membrane] [CatalystActivity:10661552] transforming growth factor beta receptor activity, type II of TGFB1:TGFBR2:TGFBR1 [plasma membrane]
(inferredTo)	[Complex:R-HSA-206874] TGFBR2 dimer:TGFB1 dimer:TGFBR1 dimer [plasma membrane] [Complex:R-HSA-170840] TGFB1:TGFBR2:TGFBR1 [plasma membrane]
(input)	[Reaction:R-XTR-170843] TGFBR2 phosphorylates TGFBR1