Reactome | Removal of aminoterminal propeptides from gamma-carboxylated proteins

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Removal of aminoterminal propeptides from gamma-carboxylated proteins Show undefined attributes

compartment	[Compartment:17963] Golgi lumen
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10729034
displayName	Removal of aminoterminal propeptides from gamma-carboxylated proteins
eventOf	[Pathway:R-XTR-159854] Gamma-carboxylation, transport, and amino-terminal cleavage of proteins - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:6678] protein processing
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-XTR-159796] Furin cleaves pro-factor IX to factor IX - Xenopus tropicalis [Reaction:R-XTR-159868] Furin cleaves pro-factor VII to factor VII - Xenopus tropicalis [Reaction:R-XTR-159733] Furin cleaves pro-factor X to factor X - Xenopus tropicalis [Reaction:R-XTR-159728] Furin cleaves pro-prothrombin to prothrombin - Xenopus tropicalis [Reaction:R-XTR-159771] Furin cleaves pro-protein C to protein C - Xenopus tropicalis [Reaction:R-XTR-159773] Furin cleaves pro-protein S to protein S - Xenopus tropicalis [Reaction:R-XTR-163798] Furin cleaves pro-protein Z to protein Z - Xenopus tropicalis [Reaction:R-XTR-163843] Furin cleaves pro-GAS6 to GAS6 - Xenopus tropicalis [Reaction:R-XTR-6807224] Furin cleaves pro-BGLAP to BGLAP - Xenopus tropicalis
inferredFrom	[Pathway:R-HSA-159782] Removal of aminoterminal propeptides from gamma-carboxylated proteins - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Removal of aminoterminal propeptides from gamma-carboxylated proteins
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-159782
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-159854] Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
(inferredTo)	[Pathway:R-HSA-159782] Removal of aminoterminal propeptides from gamma-carboxylated proteins