Reactome | PCho and CTP are condensed to CDP-Cho by PCYT1 dimer

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PCho and CTP are condensed to CDP-Cho by PCYT1 dimer Show undefined attributes

catalystActivity	[CatalystActivity:10516133] choline-phosphate cytidylyltransferase activity of PCYT1 dimer [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:10486564] Wright, Adam, 2024-03-07
dbId	10516135
displayName	PCho and CTP are condensed to CDP-Cho by PCYT1 dimer
eventOf	[Pathway:R-XTR-1483191] Synthesis of PC - Xenopus tropicalis
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-XTR-1482973] CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane - Xenopus tropicalis [Reaction:R-XTR-1482961] CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane - Xenopus tropicalis
inferredFrom	[Reaction:R-HSA-1483081] PCho and CTP are condensed to CDP-Cho by PCYT1 dimer - Homo sapiens
input	[SimpleEntity:R-ALL-110614] CTP [cytosol] [SimpleEntity:R-ALL-1524071] PCho [cytosol]
isInDisease	false
isInferred	true
name	PCho and CTP are condensed to CDP-Cho by PCYT1 dimer
output	[SimpleEntity:R-ALL-1524060] CDP-Cho [cytosol] [SimpleEntity:R-ALL-111294] PPi [cytosol]
precedingEvent	[Reaction:R-XTR-1483004] Cho is phosphorylated to PCho by CHK dimer - Xenopus tropicalis
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-1483081
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-1483191] Synthesis of PC
(precedingEvent)	[Reaction:R-XTR-1482973] CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane [Reaction:R-XTR-1482961] CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane
(inferredTo)	[Reaction:R-HSA-1483081] PCho and CTP are condensed to CDP-Cho by PCYT1 dimer