Reactome | PS is hydrolyzed to 1-acyl LPS by PLA2[9]

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PS is hydrolyzed to 1-acyl LPS by PLA2[9] Show undefined attributes

catalystActivity	[CatalystActivity:10683070] A2-type glycerophospholipase activity of PLA2(9) [cytosol]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10683072
displayName	PS is hydrolyzed to 1-acyl LPS by PLA2[9]
eventOf	[Pathway:R-XTR-1482801] Acyl chain remodelling of PS - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-XTR-1482636] 1-acyl LPS is acylated to PS by LPSAT - Xenopus tropicalis
inferredFrom	[Reaction:R-HSA-1482771] PS is hydrolyzed to 1-acyl LPS by PLA2[9] - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-1500646] PS [endoplasmic reticulum membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	PS is hydrolyzed to 1-acyl LPS by PLA2[9]
output	[SimpleEntity:R-ALL-1498724] 1-acyl LPS [endoplasmic reticulum membrane] [SimpleEntity:R-ALL-1524021] LCFA(-) [endoplasmic reticulum membrane]
precedingEvent	[Reaction:R-XTR-1483186] PC is converted to PS by PTDSS1 - Xenopus tropicalis [Reaction:R-XTR-1482636] 1-acyl LPS is acylated to PS by LPSAT - Xenopus tropicalis [Reaction:R-XTR-1483089] PE is converted to PS by PTDSS2 - Xenopus tropicalis [Reaction:R-XTR-1482691] 2-acyl LPS is acylated to PS by LPSAT - Xenopus tropicalis
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-1482771
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-1482801] Acyl chain remodelling of PS
(inferredTo)	[Reaction:R-HSA-1482771] PS is hydrolyzed to 1-acyl LPS by PLA2[9]
(precedingEvent)	[Reaction:R-XTR-1482636] 1-acyl LPS is acylated to PS by LPSAT