Reactome | MEOS oxidizes ethanol to acetaldehyde

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MEOS oxidizes ethanol to acetaldehyde Show undefined attributes

catalystActivity	[CatalystActivity:10656319] monooxygenase activity of Cytochrome P450 (CYP2E1 based) [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:17957] endoplasmic reticulum lumen [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10659446
displayName	MEOS oxidizes ethanol to acetaldehyde
eventOf	[Pathway:R-XTR-211999] CYP2E1 reactions - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-143468] MEOS oxidizes ethanol to acetaldehyde - Homo sapiens
input	[SimpleEntity:R-ALL-113748] EtOH [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-156540] H+ [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-113601] NADPH [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-113534] O2 [endoplasmic reticulum lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	MEOS oxidizes ethanol to acetaldehyde
output	[SimpleEntity:R-ALL-113745] CH3CHO [endoplasmic reticulum lumen] 2 × [SimpleEntity:R-ALL-113519] H2O [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-113564] NADP+ [endoplasmic reticulum lumen]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-143468
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-211999] CYP2E1 reactions
(inferredTo)	[Reaction:R-HSA-143468] MEOS oxidizes ethanol to acetaldehyde