Reactome | RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-XTR-1363307] RBL1:E2F4:DP1/2:Cyclin E/A:CDK2 [nucleoplasm] - Xenopus tropicalis [Complex:R-XTR-1227668] HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] - Xenopus tropicalis
consumedByEvent	[Reaction:R-XTR-1363311] p107 (RBL1) in complex with E2F4:DP1/2 binds to cyclin E/A:CDK2 - Xenopus tropicalis [Reaction:R-XTR-1226095] Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex - Xenopus tropicalis [Reaction:R-XTR-1227671] Recruitment of HDAC1 by p107 (RBL1) - Xenopus tropicalis
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10681057
displayName	RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-XTR-68664] e2f4 [nucleoplasm] [EntityWithAccessionedSequence:R-XTR-389104] rbl1 [nucleoplasm] [DefinedSet:R-XTR-1362227] TFDP1,TFDP2 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-1226088] RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] - Homo sapiens
maxDepth	3
name	RBL1:E2F4:TFDP1,TFDP2
schemaClass	Complex
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-1226088
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-XTR-1363311] p107 (RBL1) in complex with E2F4:DP1/2 binds to cyclin E/A:CDK2 [Reaction:R-XTR-1226095] Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex [Reaction:R-XTR-1227671] Recruitment of HDAC1 by p107 (RBL1)
(hasComponent)	[Complex:R-XTR-1363307] RBL1:E2F4:DP1/2:Cyclin E/A:CDK2 [nucleoplasm] [Complex:R-XTR-1227668] HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm]
(inferredTo)	[Complex:R-HSA-1226088] RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm]