Reactome | ITGA2:ITGB1 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-XTR-4086102] LUM:Integrin alpha2beta1 [plasma membrane] - Xenopus tropicalis
consumedByEvent	[Reaction:R-XTR-4085133] LUM (lumican) binds integrin alpha2beta1 - Xenopus tropicalis
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10668093
displayName	ITGA2:ITGB1 [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-XTR-57562] itga2 [plasma membrane] [EntityWithAccessionedSequence:R-XTR-57596] itgb1 [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-114561] ITGA2:ITGB1 [plasma membrane] - Homo sapiens
maxDepth	2
memberOf	[CandidateSet:R-XTR-2731104] Integrin alpha2beta1, (alpha6beta4) [plasma membrane] - Xenopus tropicalis [DefinedSet:R-XTR-2681746] Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 [plasma membrane] - Xenopus tropicalis
name	ITGA2:ITGB1
schemaClass	Complex
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-114561
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(hasMember)	[DefinedSet:R-XTR-2681746] Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 [plasma membrane] [CandidateSet:R-XTR-2731104] Integrin alpha2beta1, (alpha6beta4) [plasma membrane] [DefinedSet:R-XTR-444996] Integrin alpha1beta1, alpha2beta1, alpha10beta1 [plasma membrane]
(input)	[Reaction:R-XTR-4085133] LUM (lumican) binds integrin alpha2beta1
(hasComponent)	[Complex:R-XTR-4086102] LUM:Integrin alpha2beta1 [plasma membrane]
(inferredTo)	[Complex:R-HSA-114561] ITGA2:ITGB1 [plasma membrane]