Reactome | CD274 N-linked glycosylation in ER

Schema > Reaction > Entries

CD274 N-linked glycosylation in ER Show undefined attributes

catalystActivity	[CatalystActivity:10553868] dolichyl-diphosphooligosaccharide-protein glycotransferase activity of OST complex [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10553873
displayName	CD274 N-linked glycosylation in ER
eventOf	[Pathway:R-SSC-9931295] PD-L1(CD274) glycosylation and translocation to plasma membrane - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-SSC-9931262] Transport of N-glycosylated CD274 to Golgi - Sus scrofa
inferredFrom	[Reaction:R-HSA-9931286] CD274 N-linked glycosylation in ER - Homo sapiens
input	[SimpleEntity:R-ALL-449651] (Glc)3 (GlcNAc)2 (Man)9 (PP-Dol)1 [lumenal side of endoplasmic reticulum membrane] [EntityWithAccessionedSequence:R-SSC-9930703] CD274 [endoplasmic reticulum membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	CD274 N-linked glycosylation in ER
output	[EntityWithAccessionedSequence:R-SSC-9931256] CD274 [endoplasmic reticulum membrane]
precedingEvent	[BlackBoxEvent:R-SSC-1112514] JAK activation - Sus scrofa
regulatedBy	[PositiveRegulation:10553874] Positive regulation by 'p-Y112-CD274 [endoplasmic reticulum membrane]' [NegativeRegulation:10553875] Negative regulation by 'p-S184,T180-CD274 [endoplasmic reticulum membrane]'
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-9931286
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-9931295] PD-L1(CD274) glycosylation and translocation to plasma membrane
(precedingEvent)	[BlackBoxEvent:R-SSC-9931262] Transport of N-glycosylated CD274 to Golgi
(inferredTo)	[Reaction:R-HSA-9931286] CD274 N-linked glycosylation in ER