Reactome | TASL recruits IRF5

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TASL recruits IRF5 Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol [Compartment:1660541] endolysosome membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10552741
displayName	TASL recruits IRF5
eventOf	[Pathway:R-SSC-9860276] SLC15A4:TASL-dependent IRF5 activation - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-9860292] Activated IKBKB phosphorylates IRF5 - Sus scrofa
inferredFrom	[Reaction:R-HSA-9860290] TASL recruits IRF5 - Homo sapiens
input	[EntityWithAccessionedSequence:R-SSC-1015676] IRF5 [cytosol] [Complex:R-SSC-9860291] SLC15A4:p-S294-TASL [endolysosome membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	TASL recruits IRF5
output	[Complex:R-SSC-9860255] SLC15A4:p-S-TASL:IRF5 [endolysosome membrane]
precedingEvent	[Reaction:R-SSC-9860264] TASL is phosphorylated - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-9860290
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-9860276] SLC15A4:TASL-dependent IRF5 activation
(precedingEvent)	[Reaction:R-SSC-9860292] Activated IKBKB phosphorylates IRF5
(inferredTo)	[Reaction:R-HSA-9860290] TASL recruits IRF5