Reactome | PANK4 hydrolyzes PPANT to pantetheine

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PANK4 hydrolyzes PPANT to pantetheine Show undefined attributes

catalystActivity	[CatalystActivity:10551312] phosphatase activity of PANK4 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10551314
displayName	PANK4 hydrolyzes PPANT to pantetheine
eventOf	[Pathway:R-SSC-199220] Vitamin B5 (pantothenate) metabolism - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9837419] PANK4 hydrolyzes PPANT to pantetheine - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-196767] PPANT [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	PANK4 hydrolyzes PPANT to pantetheine (R)-4'-phosphopantetheine + H2O => (R)-pantetheine + phosphate
output	[SimpleEntity:R-ALL-8938313] Pantetheine [cytosol] [SimpleEntity:R-ALL-29372] Pi [cytosol]
precedingEvent	[Reaction:R-SSC-196840] 3xPPCDC:3FMN decarboxylates PPC - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-9837419
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-199220] Vitamin B5 (pantothenate) metabolism
(inferredTo)	[Reaction:R-HSA-9837419] PANK4 hydrolyzes PPANT to pantetheine

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