Reactome | p-S172-TBK1:p-S177-OPTN:K63polyUb-mitochondrial proteins [mitochondrial outer membrane]

Schema > Complex > Entries

compartment	[Compartment:17906] mitochondrial outer membrane
componentOf	[Complex:R-SSC-9840806] ATG9A:p-S172-TBK1:p-S177-OPTN:K63polyUb-mitochondrial proteins [mitochondrial outer membrane] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-9840807] OPTN binds ATG9A - Sus scrofa [Reaction:R-SSC-9824892] MAP1LC3B binds p-S-OPTN bound to Ub-mitochondria - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10550793
displayName	p-S172-TBK1:p-S177-OPTN:K63polyUb-mitochondrial proteins [mitochondrial outer membrane]
hasComponent	[DefinedSet:R-SSC-9824893] K63polyUb-MOM proteins [mitochondrial outer membrane] [EntityWithAccessionedSequence:R-SSC-168379] phospho-p-S172-TBK1 [cytosol] [EntityWithAccessionedSequence:R-SSC-9687840] phospho-p-S177,S473,S513-OPTN [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-9824890] p-S172-TBK1:p-S177-OPTN:K63polyUb-mitochondrial proteins [mitochondrial outer membrane] - Homo sapiens
maxDepth	3
name	p-S172-TBK1:p-S177-OPTN:K63polyUb-mitochondrial proteins
producedByEvent	[Reaction:R-SSC-9824897] p-S-TBK1 phosphorylates OPTN - Sus scrofa
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-9824890
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-SSC-9840807] OPTN binds ATG9A [Reaction:R-SSC-9824892] MAP1LC3B binds p-S-OPTN bound to Ub-mitochondria
(hasComponent)	[Complex:R-SSC-9840806] ATG9A:p-S172-TBK1:p-S177-OPTN:K63polyUb-mitochondrial proteins [mitochondrial outer membrane] [Complex:R-SSC-9824895] MAP1LC3B:p-S-TBK1:p-S-OPTN:K63polyUb-mitochondrial proteins [mitochondrial outer membrane]
(output)	[Reaction:R-SSC-9824897] p-S-TBK1 phosphorylates OPTN
(inferredTo)	[Complex:R-HSA-9824890] p-S172-TBK1:p-S177-OPTN:K63polyUb-mitochondrial proteins [mitochondrial outer membrane]

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