Reactome | Formation of the core cleavage and polyadenylation complex

Schema > Reaction > Entries

Formation of the core cleavage and polyadenylation complex Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10549799
displayName	Formation of the core cleavage and polyadenylation complex
eventOf	[Pathway:R-SSC-9770562] mRNA Polyadenylation - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-9970141] Core CPA complex binds capped pre-mRNA - Sus scrofa
inferredFrom	[Reaction:R-HSA-9770123] Formation of the core cleavage and polyadenylation complex - Homo sapiens
input	[Complex:R-SSC-9770676] CF I [nucleoplasm] [Complex:R-SSC-9770773] CPSF [nucleoplasm] [Complex:R-SSC-9970107] CSTF hexamer [nucleoplasm] [EntityWithAccessionedSequence:R-SSC-4615988] SYMPK [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Formation of the core cleavage and polyadenylation complex
output	[Complex:R-SSC-9970121] Core CPA complex [nucleoplasm]
precedingEvent	[Reaction:R-SSC-9770557] Formation of the CF I complex - Sus scrofa [Reaction:R-SSC-9770559] Formation of the CSTF complex - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-9770123
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-9770562] mRNA Polyadenylation
(precedingEvent)	[Reaction:R-SSC-9970141] Core CPA complex binds capped pre-mRNA
(inferredTo)	[Reaction:R-HSA-9770123] Formation of the core cleavage and polyadenylation complex

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