Reactome | GLRA:GLRB:Gly transports extracellular Cl- to cytosol

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GLRA:GLRB:Gly transports extracellular Cl- to cytosol Show undefined attributes

catalystActivity	[CatalystActivity:10486124] extracellularly glycine-gated chloride channel activity of GLRA:GLRB:Gly [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10486126
displayName	GLRA:GLRB:Gly transports extracellular Cl- to cytosol
eventOf	[Pathway:R-SSC-112314] Neurotransmitter receptors and postsynaptic signal transmission - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-975389] GLRA:GLRB:Gly transports extracellular Cl- to cytosol - Homo sapiens
input	[SimpleEntity:R-ALL-188972] Cl- [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	GLRA:GLRB:Gly transports extracellular Cl- to cytosol The glycine receptor complex is permeable to Cl- when glycine binds to it
output	[SimpleEntity:R-ALL-352022] Cl- [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-975389
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-112314] Neurotransmitter receptors and postsynaptic signal transmission
(inferredTo)	[Reaction:R-HSA-975389] GLRA:GLRB:Gly transports extracellular Cl- to cytosol

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