Reactome | MTTP binds lomitapide

Schema > Reaction > Entries

category	binding
compartment	[Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10549006
displayName	MTTP binds lomitapide
eventOf	[Pathway:R-SSC-8964041] LDL remodeling - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9737780] MTTP binds lomitapide - Homo sapiens
input	[ChemicalDrug:R-ALL-9737774] lomitapide [endoplasmic reticulum lumen] [Complex:R-SSC-174681] MTTP:PDI:lipid complex [endoplasmic reticulum lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	MTTP binds lomitapide
output	[Complex:R-SSC-9737771] MTTP:lomitapide [endoplasmic reticulum lumen]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-9737780
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-8964041] LDL remodeling
(inferredTo)	[Reaction:R-HSA-9737780] MTTP binds lomitapide

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