Reactome | HCNs:cAMP bind SNIs

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10548773
displayName	HCNs:cAMP bind SNIs
eventOf	[Pathway:R-SSC-1296061] HCN channels - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9726875] HCNs:cAMP bind SNIs - Homo sapiens
input	[Complex:R-SSC-1297435] HCNs:cAMP [plasma membrane] [CandidateSet:R-ALL-9726901] SNIs [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	HCNs:cAMP bind SNIs HCN1-4:cAMP bind Sinus Node Inhibitors
output	[Complex:R-SSC-9726872] HCNs:cAMP:SNIs [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-9726875
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-1296061] HCN channels
(inferredTo)	[Reaction:R-HSA-9726875] HCNs:cAMP bind SNIs

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