Reactome | DRD2 antagonist drugs bind to DRD2

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10546544
displayName	DRD2 antagonist drugs bind to DRD2
eventOf	[Pathway:R-SSC-390651] Dopamine receptors - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9654054] DRD2 antagonist drugs bind to DRD2 - Homo sapiens
input	[EntityWithAccessionedSequence:R-SSC-390816] DRD2 [plasma membrane] [DefinedSet:R-ALL-9653947] DRD2 antagonists [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	DRD2 antagonist drugs bind to DRD2
output	[Complex:R-SSC-9653982] DRD2:DRD2 antagonists [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-9654054
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-390651] Dopamine receptors
(inferredTo)	[Reaction:R-HSA-9654054] DRD2 antagonist drugs bind to DRD2

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