Reactome | HTR3A pentamer:5HT transports Na+,K+,Ca2+

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HTR3A pentamer:5HT transports Na+,K+,Ca2+ Show undefined attributes

catalystActivity	[CatalystActivity:10546456] serotonin-gated monoatomic cation channel activity of HTR3A pentamer:5HT [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10546458
displayName	HTR3A pentamer:5HT transports Na+,K+,Ca2+
eventOf	[Pathway:R-SSC-112314] Neurotransmitter receptors and postsynaptic signal transmission - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9648983] HTR3A pentamer:5HT transports Na+,K+,Ca2+ - Homo sapiens
input	[SimpleEntity:R-ALL-74112] Ca2+ [extracellular region] [SimpleEntity:R-ALL-74126] K+ [extracellular region] [SimpleEntity:R-ALL-74113] Na+ [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	HTR3A pentamer:5HT transports Na+,K+,Ca2+
output	[SimpleEntity:R-ALL-74016] Ca2+ [cytosol] [SimpleEntity:R-ALL-29804] K+ [cytosol] [SimpleEntity:R-ALL-83910] Na+ [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-9648983
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-112314] Neurotransmitter receptors and postsynaptic signal transmission
(inferredTo)	[Reaction:R-HSA-9648983] HTR3A pentamer:5HT transports Na+,K+,Ca2+

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