Reactome | IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-SSC-913415] High affinity IL-5 receptor complex dimer, inactive JAK2 [plasma membrane] - Sus scrofa [Complex:R-SSC-913415] High affinity IL-5 receptor complex dimer, inactive JAK2 [plasma membrane] - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10482963
displayName	IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane]
hasComponent	[Complex:R-SSC-879945] IL3RB:JAK2 [plasma membrane] [Complex:R-SSC-450056] IL5 homodimer:IL5RA [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-913423] IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] - Homo sapiens
maxDepth	4
memberOf	[DefinedSet:R-SSC-913364] High affinity binding complexes of interleukin receptors using the Common beta chain [plasma membrane] - Sus scrofa [DefinedSet:R-SSC-904816] Tyrosine kinases that phosphorylate the Common beta chain [plasma membrane] - Sus scrofa
name	IL5 homodimer:IL5RA:Common beta chain:JAK2
producedByEvent	[Reaction:R-SSC-913370] Interleukin-5:Interleukin-5 receptor alpha binds IL3RB:JAK2 - Sus scrofa
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-913423
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(hasMember)	[DefinedSet:R-SSC-913364] High affinity binding complexes of interleukin receptors using the Common beta chain [plasma membrane] [DefinedSet:R-SSC-904816] Tyrosine kinases that phosphorylate the Common beta chain [plasma membrane]
(output)	[Reaction:R-SSC-913370] Interleukin-5:Interleukin-5 receptor alpha binds IL3RB:JAK2
(hasComponent)	[Complex:R-SSC-913415] High affinity IL-5 receptor complex dimer, inactive JAK2 [plasma membrane]
(inferredTo)	[Complex:R-HSA-913423] IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane]