Reactome | PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3

Schema > Reaction > Entries

PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3 Show undefined attributes

category	binding
compartment	[Compartment:17947] peroxisomal membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10544832
displayName	PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3
eventOf	[Pathway:R-SSC-9033241] Peroxisomal protein import - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-9033485] PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11 - Sus scrofa
inferredFrom	[Reaction:R-HSA-9033527] PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3 - Homo sapiens
input	[Complex:R-SSC-9033513] PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] [Complex:R-SSC-8953915] Ub:UBE2D1,2,3 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3
output	[Complex:R-SSC-9033521] PEX2:PEX10:PEX12:PEX5L:Ub:UBE2D1,2,3:PEX7:PEX13:PEX14 [peroxisomal membrane]
precedingEvent	[BlackBoxEvent:R-SSC-9033514] Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-9033527
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-9033241] Peroxisomal protein import
(precedingEvent)	[Reaction:R-SSC-9033485] PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11
(inferredTo)	[Reaction:R-HSA-9033527] PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3

Cite Us!