Reactome | Acitretin binds to RAR:RXR

Schema > Reaction > Entries

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10543084
displayName	Acitretin binds to RAR:RXR
eventOf	[Pathway:R-SSC-5362517] Signaling by Retinoic Acid - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9009817] Acitretin binds to RAR:RXR - Homo sapiens
input	[ChemicalDrug:R-ALL-9009800] acitretin [nucleoplasm] [Complex:R-SSC-5334844] RARA:RXRA [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Acitretin binds to RAR:RXR
output	[Complex:R-SSC-9009787] RAR:RXR:acitretin [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-9009817
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-5362517] Signaling by Retinoic Acid
(inferredTo)	[Reaction:R-HSA-9009817] Acitretin binds to RAR:RXR

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