Reactome | NCOA3 binds ESR1:estrogen:TFGA gene

Schema > Reaction > Entries

NCOA3 binds ESR1:estrogen:TFGA gene Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10542940
displayName	NCOA3 binds ESR1:estrogen:TFGA gene
eventOf	[Pathway:R-SSC-9018519] Estrogen-dependent gene expression - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-9008285] NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 - Sus scrofa
inferredFrom	[Reaction:R-HSA-9008258] NCOA3 binds ESR1:estrogen:TFGA gene - Homo sapiens
input	[Complex:R-SSC-9008287] ESR1 dimer:estrogen:TGFA gene promoter [nucleoplasm] 2 × [EntityWithAccessionedSequence:R-SSC-442488] NCOA3 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	NCOA3 binds ESR1:estrogen:TFGA gene
output	[Complex:R-SSC-9008244] ESR1:estrogen:ERE:NCOA3:TFGA gene [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-9008258
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-9018519] Estrogen-dependent gene expression
(precedingEvent)	[Reaction:R-SSC-9008285] NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3
(inferredTo)	[Reaction:R-HSA-9008258] NCOA3 binds ESR1:estrogen:TFGA gene

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