Reactome | IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5

Schema > BlackBoxEvent > Entries

IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5 Show undefined attributes

category	omitted
compartment	[Compartment:70101] cytosol [Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10542826
displayName	IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5
eventOf	[Pathway:R-SSC-8854691] Interleukin-20 family signaling - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-SSC-8986985] IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 - Sus scrofa
inferredFrom	[BlackBoxEvent:R-HSA-8987266] IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5 - Homo sapiens
input	[Complex:R-SSC-8987203] IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] [DefinedSet:R-SSC-9009216] STAT1, STAT2, STAT3, STAT4, STAT5 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5
output	[Complex:R-SSC-8987135] IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1,STAT2, STAT3, STAT4, STAT5 [plasma membrane]
precedingEvent	[Reaction:R-SSC-8987040] IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 - Sus scrofa
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:49633] Sus scrofa
stId	R-SSC-8987266
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-8854691] Interleukin-20 family signaling
(precedingEvent)	[BlackBoxEvent:R-SSC-8986985] IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5
(inferredTo)	[BlackBoxEvent:R-HSA-8987266] IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5

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