Reactome | IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3

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IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 Show undefined attributes

catalystActivity	[CatalystActivity:10542822] transmembrane receptor protein tyrosine kinase activity of IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 [plasma membrane]
category	omitted
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10542824
displayName	IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3
eventOf	[Pathway:R-SSC-8854691] Interleukin-20 family signaling - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-SSC-8987230] p-STAT1 and p-STAT3 dissociates from IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 - Sus scrofa
inferredFrom	[BlackBoxEvent:R-HSA-8987255] IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 - Homo sapiens
input	2 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-SSC-8987258] IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	STAT1,STAT3 are phosphorylated by IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1 STAT1,STAT3 are phosphorylated by IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1 STAT1,STAT3 are phosphorylated by IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1 STAT1,STAT3 are phosphorylated by IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1
output	2 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-SSC-8987110] IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:p-STAT1, p-STAT3 [plasma membrane]
precedingEvent	[BlackBoxEvent:R-SSC-8987080] IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 binds STAT1, STAT3 - Sus scrofa
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:49633] Sus scrofa
stId	R-SSC-8987255
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-8854691] Interleukin-20 family signaling
(precedingEvent)	[BlackBoxEvent:R-SSC-8987230] p-STAT1 and p-STAT3 dissociates from IL26:IL10RB:p-TYK2:IL20RA:p-JAK1
(inferredTo)	[BlackBoxEvent:R-HSA-8987255] IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3

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