Reactome | C2orf47:AFG3L2 binds the transit peptide of SMDT1

Schema > Reaction > Entries

C2orf47:AFG3L2 binds the transit peptide of SMDT1 Show undefined attributes

category	binding
compartment	[Compartment:70616] mitochondrial inner membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10539991
displayName	C2orf47:AFG3L2 binds the transit peptide of SMDT1
eventOf	[Pathway:R-SSC-8949664] Processing of SMDT1 - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-8949649] PMPCA:PMPCB cleaves the transit peptide of proSMDT1 (proEMRE) - Sus scrofa
inferredFrom	[Reaction:R-HSA-8949661] C2orf47:AFG3L2 binds the transit peptide of SMDT1 - Homo sapiens
input	[Complex:R-SSC-8949645] C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane] [EntityWithAccessionedSequence:R-SSC-8949655] SMDT1 [mitochondrial inner membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	C2orf47:AFG3L2 binds the transit peptide of SMDT1
output	[Complex:R-SSC-8949643] proSMDT1:C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-8949661
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-8949664] Processing of SMDT1
(precedingEvent)	[Reaction:R-SSC-8949649] PMPCA:PMPCB cleaves the transit peptide of proSMDT1 (proEMRE)
(inferredTo)	[Reaction:R-HSA-8949661] C2orf47:AFG3L2 binds the transit peptide of SMDT1

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