Reactome | F- and N- BAR domain proteins bind the clathrin-coated pit

Schema > Reaction > Entries

F- and N- BAR domain proteins bind the clathrin-coated pit Show undefined attributes

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10536200
displayName	F- and N- BAR domain proteins bind the clathrin-coated pit
eventOf	[Pathway:R-SSC-8856828] Clathrin-mediated endocytosis - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-8868230] SNX9 recruits components of the actin polymerizing machinery - Sus scrofa
inferredFrom	[Reaction:R-HSA-8867754] F- and N- BAR domain proteins bind the clathrin-coated pit - Homo sapiens
input	[Complex:R-SSC-8868606] AMPH:BIN1 [cytosol] [Complex:R-SSC-8868046] FNBP1 dimer [cytosol] [Complex:R-SSC-8868045] FNBP1L dimer [cytosol] [CandidateSet:R-SSC-8868621] PACSIN dimers [cytosol] [Complex:R-SSC-8868051] PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] [CandidateSet:R-SSC-8867746] SH3GLs [cytosol] [CandidateSet:R-SSC-8868040] SNX9,18 [cytosol] [Complex:R-SSC-8868042] TRIP10 dimer [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	F- and N- BAR domain proteins bind the clathrin-coated pit
output	[DefinedSet:R-SSC-8862270] FCHO1,2 dimer [cytosol] [Complex:R-SSC-8867751] PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] [EntityWithAccessionedSequence:R-SSC-1604624] PIK3C2A [cytosol]
precedingEvent	[Reaction:R-SSC-8868071] Clathrin recruits PIK3C2A - Sus scrofa
regulatedBy	[PositiveRegulation:R-HSA-8868077] Positive regulation by 'PI(3,4)P2 [plasma membrane]'
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-8867754
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-8856828] Clathrin-mediated endocytosis
(precedingEvent)	[Reaction:R-SSC-8868230] SNX9 recruits components of the actin polymerizing machinery
(inferredTo)	[Reaction:R-HSA-8867754] F- and N- BAR domain proteins bind the clathrin-coated pit