Reactome | RUNX2:CBFB [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-SSC-8877936] RUNX2:CBFB:p-2S-SMAD1:p-2S-SMAD1:SMAD4 [nucleoplasm] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-9009282] CDK1 phosphorylates RUNX2 - Sus scrofa [Reaction:R-SSC-9008412] CDK4 phosphorylates RUNX2 - Sus scrofa [Reaction:R-SSC-8877941] RUNX2 binds SMAD1 in the nucleus - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10537847
displayName	RUNX2:CBFB [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-SSC-8865293] CBFB [nucleoplasm] [EntityWithAccessionedSequence:R-SSC-9007689] RUNX2 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-8865420] RUNX2:CBFB [nucleoplasm] - Homo sapiens
maxDepth	2
memberOf	[CandidateSet:R-SSC-9008881] RUNX2:CBFB,p-S451-RUNX2:CBFB,(p-2S-RUNX2:CBFB) [nucleoplasm] - Sus scrofa
name	RUNX2:CBFB
producedByEvent	[Reaction:R-SSC-9008822] PPM1D dephosphorylates RUNX2 - Sus scrofa
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-8865420
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[Reaction:R-SSC-9008822] PPM1D dephosphorylates RUNX2
(input)	[Reaction:R-SSC-9009282] CDK1 phosphorylates RUNX2 [Reaction:R-SSC-8877941] RUNX2 binds SMAD1 in the nucleus [Reaction:R-SSC-9008412] CDK4 phosphorylates RUNX2
(hasComponent)	[Complex:R-SSC-8877936] RUNX2:CBFB:p-2S-SMAD1:p-2S-SMAD1:SMAD4 [nucleoplasm]
(hasMember)	[CandidateSet:R-SSC-9008881] RUNX2:CBFB,p-S451-RUNX2:CBFB,(p-2S-RUNX2:CBFB) [nucleoplasm]
(inferredTo)	[Complex:R-HSA-8865420] RUNX2:CBFB [nucleoplasm]