Reactome | CL-LK binds carbohydrates on target cell surface

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CL-LK binds carbohydrates on target cell surface Show undefined attributes

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10534072
displayName	CL-LK binds carbohydrates on target cell surface
eventOf	[Pathway:R-SSC-166662] Lectin pathway of complement activation - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8852509] CL-LK binds carbohydrates on target cell surface - Homo sapiens
input	[OtherEntity:R-ALL-166718] Bacterial mannose surface pattern [plasma membrane] 4 × [SimpleEntity:R-ALL-74112] Ca2+ [extracellular region] [Complex:R-SSC-8852513] CL-LK:MASP1 dimer:MASP2 dimer [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	CL-LK binds carbohydrates on target cell surface
output	[Complex:R-SSC-8852493] CL-LK:MASP1 dimer:MASP2 dimer:Bacterial mannose surface pattern:4xCa2+ [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-8852509
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-166662] Lectin pathway of complement activation
(inferredTo)	[Reaction:R-HSA-8852509] CL-LK binds carbohydrates on target cell surface

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