Reactome | NTPDase3 hydrolyzes nucleoside diphosphates

Schema > Reaction > Entries

NTPDase3 hydrolyzes nucleoside diphosphates Show undefined attributes

catalystActivity	[CatalystActivity:10533597] nucleoside diphosphate phosphatase activity of NTPDase3:Ca2+,Mg2+ [plasma membrane]
category	transition
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10533599
displayName	NTPDase3 hydrolyzes nucleoside diphosphates
eventOf	[Pathway:R-SSC-8850843] Phosphate bond hydrolysis by NTPDase proteins - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8851129] NTPDase3 hydrolyzes nucleoside diphosphates - Homo sapiens
input	[SimpleEntity:R-ALL-109276] H2O [extracellular region] [SimpleEntity:R-ALL-8870906] NDP [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	NTPDase3 hydrolyzes nucleoside diphosphates a ribonucleoside 5'-diphosphate + H2O => a ribonucleoside 5'-phosphate + phosphate + H(+)
output	[SimpleEntity:R-ALL-351626] H+ [extracellular region] [SimpleEntity:R-ALL-8870962] NMP [extracellular region] [SimpleEntity:R-ALL-109277] Pi [extracellular region]
precedingEvent	[Reaction:R-SSC-8851110] NTPDase3 hydrolyzes nucleoside triphosphates - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-8851129
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-8850843] Phosphate bond hydrolysis by NTPDase proteins
(inferredTo)	[Reaction:R-HSA-8851129] NTPDase3 hydrolyzes nucleoside diphosphates

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