Reactome | PTPN1 binds PTK6

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10533200
displayName	PTPN1 binds PTK6
eventOf	[Pathway:R-SSC-8849472] PTK6 Down-Regulation - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-8849435] PTPN1 dephosphorylates PTK6 - Sus scrofa
inferredFrom	[Reaction:R-HSA-8849428] PTPN1 binds PTK6 - Homo sapiens
input	[EntityWithAccessionedSequence:R-SSC-8848007] phospho-p-Y342-PTK6 [cytosol] [EntityWithAccessionedSequence:R-SSC-210625] PTPN1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	PTPN1 binds PTK6
output	[Complex:R-SSC-8849424] p-Y342-PTK6:PTPN1 [cytosol]
precedingEvent	[Reaction:R-SSC-8848005] ERBB2 promotes PTK6 autophosphorylation - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-8849428
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-8849472] PTK6 Down-Regulation
(precedingEvent)	[Reaction:R-SSC-8849435] PTPN1 dephosphorylates PTK6
(inferredTo)	[Reaction:R-HSA-8849428] PTPN1 binds PTK6

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