Reactome | Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm

Schema > Reaction > Entries

category	transition
compartment	[Compartment:13231] nuclear envelope
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10452546
displayName	Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm
eventOf	[Pathway:R-SSC-75815] Ubiquitin-dependent degradation of Cyclin D - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-75822] Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm - Homo sapiens
input	[Complex:R-SSC-75812] phospho(T286)-Cyclin D1:Cdk4 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm
output	[Complex:R-SSC-75814] phospho(T286)-Cyclin D1:Cdk4 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-75822
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-75815] Ubiquitin-dependent degradation of Cyclin D
(inferredTo)	[Reaction:R-HSA-75822] Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm

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