Reactome | GAR + 10-Formyl-THF => FGAR + THF

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GAR + 10-Formyl-THF => FGAR + THF Show undefined attributes

catalystActivity	[CatalystActivity:10451118] phosphoribosylglycinamide formyltransferase activity of GART [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10451120
displayName	GAR + 10-Formyl-THF => FGAR + THF
eventOf	[Pathway:R-SSC-73817] Purine ribonucleoside monophosphate biosynthesis - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-73813] GAR + 10-Formyl-THF => FGAR + THF - Homo sapiens
input	[SimpleEntity:R-ALL-419151] 10-formyl-THF [cytosol] [SimpleEntity:R-ALL-111338] PRGA [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	GAR + 10-Formyl-THF => FGAR + THF N(1)-(5-phospho-beta-D-ribosyl)glycinamide + (6R)-10-formyltetrahydrofolate => N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide + (6S)-5,6,7,8-tetrahydrofolate + H(+) 5-phosphoribosylglycinamide (GAR) + 10-formyl-tetrahydrofolate => 5'-phosphoribosylformylglycinamide (FGAR) + tetrahydrofolate
output	[SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-111354] N-Formyl-GAR [cytosol] [SimpleEntity:R-ALL-111355] THF [cytosol]
precedingEvent	[Reaction:R-SSC-73814] 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-73813
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-73817] Purine ribonucleoside monophosphate biosynthesis
(inferredTo)	[Reaction:R-HSA-73813] GAR + 10-Formyl-THF => FGAR + THF

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