Reactome | Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs

Schema > Reaction > Entries

Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs Show undefined attributes

category	binding
compartment	[Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10531883
displayName	Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs
eventOf	[Pathway:R-SSC-6811434] COPI-dependent Golgi-to-ER retrograde traffic - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-6811423] Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs - Homo sapiens
input	[Complex:R-SSC-6811358] NBAS:RINT1:ZW10 [cytosol] [Complex:R-SSC-6811381] RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] [Complex:R-SSC-6811340] STX18:USE1L:BNIP1 [endoplasmic reticulum membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs
output	[Complex:R-SSC-983245] Kinesins:microtubule [cytosol] [Complex:R-SSC-6811379] RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo:NBAS:RINT1:ZW10:STX18:USE1L:BNIP1 [endoplasmic reticulum membrane]
precedingEvent	[Reaction:R-SSC-6811426] Retrograde COPI vesicles bind kinesin and microtubules - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-6811423
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-6811434] COPI-dependent Golgi-to-ER retrograde traffic
(inferredTo)	[Reaction:R-HSA-6811423] Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs

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