Reactome | NME1:NME3 heterohexamer phosphorylates NDPs to NTPs

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NME1:NME3 heterohexamer phosphorylates NDPs to NTPs Show undefined attributes

catalystActivity	[CatalystActivity:10530363] nucleoside diphosphate kinase activity of NME1:NME3 heterohexamer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10530365
displayName	NME1:NME3 heterohexamer phosphorylates NDPs to NTPs
eventOf	[Pathway:R-SSC-499943] Interconversion of nucleotide di- and triphosphates - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-6806877] NME1:NME3 heterohexamer phosphorylates NDPs to NTPs - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-8866401] NDP(3-) [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	NME1:NME3 heterohexamer phosphorylates NDPs to NTPs a ribonucleoside 5'-diphosphate + ATP => a ribonucleoside 5'-triphosphate + ADP
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-6806881] NTP [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-6806877
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-499943] Interconversion of nucleotide di- and triphosphates
(inferredTo)	[Reaction:R-HSA-6806877] NME1:NME3 heterohexamer phosphorylates NDPs to NTPs

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