Reactome | AURKB binds TP53

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AURKB binds TP53 Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10529878
displayName	AURKB binds TP53
eventOf	[Pathway:R-SSC-6804756] Regulation of TP53 Activity through Phosphorylation - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-6805126] AURKB phosphorylates TP53 - Sus scrofa
inferredFrom	[Reaction:R-HSA-6805122] AURKB binds TP53 - Homo sapiens
input	[EntityWithAccessionedSequence:R-SSC-4655360] AURKB [nucleoplasm] [Complex:R-SSC-3222134] NOC2L:p-S15,S20-TP53 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	AURKB binds TP53
output	[Complex:R-SSC-6805123] AURKB:NOC2L:p-S15,S20-TP53 [nucleoplasm]
precedingEvent	[Reaction:R-SSC-3222128] NOC2L binds TP53 - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-6805122
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-6804756] Regulation of TP53 Activity through Phosphorylation
(precedingEvent)	[Reaction:R-SSC-6805126] AURKB phosphorylates TP53
(inferredTo)	[Reaction:R-HSA-6805122] AURKB binds TP53