Reactome | Homer1,2,3 binds mGluR1a,5

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10525835
displayName	Homer1,2,3 binds mGluR1a,5
eventOf	[Pathway:R-SSC-6794361] Neurexins and neuroligins - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-6794347] Homer1,2,3 dimerizes - Sus scrofa
inferredFrom	[Reaction:R-HSA-6794355] Homer1,2,3 binds mGluR1a,5 - Homo sapiens
input	[DefinedSet:R-SSC-6794289] GRM1,GRM5 [plasma membrane] [DefinedSet:R-SSC-6794285] HOMER1,2,3 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Homer1,2,3 binds mGluR1a,5
output	[Complex:R-SSC-6794305] HOMER1,2,3:GRM1,GRM5 [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-6794355
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-6794361] Neurexins and neuroligins
(precedingEvent)	[Reaction:R-SSC-6794347] Homer1,2,3 dimerizes
(inferredTo)	[Reaction:R-HSA-6794355] Homer1,2,3 binds mGluR1a,5

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