Reactome | MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA:Unhooking nucleases [nucleoplasm]

Schema > Complex > Entries

MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA:Unhooking nucleases [nucleoplasm] Show undefined attributes

catalystActivities	[CatalystActivity:10524646] DNA nuclease activity of MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA:Unhooking nucleases [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[BlackBoxEvent:R-SSC-6785986] DNA nucleases unhook the interstrand crosslink (ICL) - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10524582
displayName	MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA:Unhooking nucleases [nucleoplasm]
hasComponent	[CandidateSet:R-SSC-6785737] DCLRE1A,DCLRE1B [nucleoplasm] [Complex:R-SSC-109943] ERCC1:ERCC4 [nucleoplasm] [Complex:R-SSC-6785733] FAN1 dimer [nucleoplasm] [Complex:R-SSC-6785367] MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA [nucleoplasm] [Complex:R-SSC-5686474] SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-6785734] MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA:Unhooking nucleases [nucleoplasm] - Homo sapiens
maxDepth	7
name	MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA:Unhooking nucleases
producedByEvent	[Reaction:R-SSC-6785732] DNA nucleases bind monoubiquitinated ID2 complex - Sus scrofa
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-6785734
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(input)	[BlackBoxEvent:R-SSC-6785986] DNA nucleases unhook the interstrand crosslink (ICL)
(physicalEntity)	[CatalystActivity:10524646] DNA nuclease activity of MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA:Unhooking nucleases [nucleoplasm]
(output)	[Reaction:R-SSC-6785732] DNA nucleases bind monoubiquitinated ID2 complex
(inferredTo)	[Complex:R-HSA-6785734] MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA:Unhooking nucleases [nucleoplasm]

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