Reactome | JAKs:LIFR [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-SSC-6783635] LIF:LIFR:JAKs [plasma membrane] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-6783681] LIF binds LIFR - Sus scrofa [Reaction:R-SSC-5696482] CTF1 binds LIFR:JAKs - Sus scrofa [Reaction:R-SSC-6783556] LIFR:JAKs bind gp130:JAKs:CNTFR - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10523165
displayName	JAKs:LIFR [plasma membrane]
hasComponent	[CandidateSet:R-SSC-1067656] JAK1, JAK2, (TYK2) [cytosol] [EntityWithAccessionedSequence:R-SSC-5693181] LIFR [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-6784198] JAKs:LIFR [plasma membrane] - Homo sapiens
maxDepth	3
memberOf	[DefinedSet:R-SSC-6783627] LIFR:JAKs,OSMR:JAKs [plasma membrane] - Sus scrofa
name	JAKs:LIFR
producedByEvent	[Reaction:R-SSC-6784189] JAKs bind LIFR - Sus scrofa
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-6784198
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[Reaction:R-SSC-6784189] JAKs bind LIFR
(hasMember)	[DefinedSet:R-SSC-6783627] LIFR:JAKs,OSMR:JAKs [plasma membrane]
(hasComponent)	[Complex:R-SSC-6783635] LIF:LIFR:JAKs [plasma membrane] [Complex:R-SSC-6783533] CTF1:LIFR:JAKs [plasma membrane] [Complex:R-SSC-6783544] CNTF:CNTFR,CRLF1:CLCF1:CNTFR:gp130:JAKs:LIFR:JAKs [plasma membrane]
(input)	[Reaction:R-SSC-6783681] LIF binds LIFR [Reaction:R-SSC-5696482] CTF1 binds LIFR:JAKs [Reaction:R-SSC-6783556] LIFR:JAKs bind gp130:JAKs:CNTFR
(inferredTo)	[Complex:R-HSA-6784198] JAKs:LIFR [plasma membrane]