Reactome | TC-NER incision complex [nucleoplasm]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10395729] endodeoxyribonuclease activity of TC-NER incision complex [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-SSC-6782204] 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER - Sus scrofa
created	[InstanceEdit:10314670] Wright, Adam, 2024-03-07
dbId	10395724
displayName	TC-NER incision complex [nucleoplasm]
hasComponent	[Complex:R-SSC-109943] ERCC1:ERCC4 [nucleoplasm] [Complex:R-SSC-6782134] TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-6782142] TC-NER incision complex [nucleoplasm] - Homo sapiens
name	TC-NER incision complex
producedByEvent	[Reaction:R-SSC-6782141] Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER - Sus scrofa
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-6782142
summation	[Summation:9864367] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-SSC-6782204] 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER
(physicalEntity)	[CatalystActivity:10395729] endodeoxyribonuclease activity of TC-NER incision complex [nucleoplasm]
(output)	[Reaction:R-SSC-6782141] Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER
(inferredTo)	[Complex:R-HSA-6782142] TC-NER incision complex [nucleoplasm]